Supplements

MOTs-C

Overview

MOTS-c earns low scores primarily due to limited human evidence despite robust preclinical data. Mouse studies (e.g., 0.5 mg/kg/day IP for 8 weeks prevented obesity, enhanced glucose uptake in soleus muscle via AICAR/AMPK; PubMed 25738459) suggest metabolic benefits akin to exercise or metformin, with reviews highlighting potential for diabetes/obesity (PubMed 36761202). However, no human RCTs confirm efficacy, only observational levels and analog safety (CB4211 phase 1). Safety score reflects a

Key strengths

Our analysis

MOTS-c is an intriguing research peptide with strong animal data for metabolic optimization but zero human efficacy trials. FDA safety concerns, sports prohibition, and impurity risks make it unsuitable for consumer use. Opt for evidence-based alternatives like diet, exercise, or approved medications.

Frequently asked questions

Is MOTs-C worth buying?
MOTs-C has a Verify Influencers trust score of 25/100 based on ingredient quality, clinical evidence, and third-party testing.
What is the trust score for MOTs-C?
MOTs-C scored 25 out of 100 in our science-backed analysis, which evaluates ingredient dosages against clinical literature and manufacturing transparency.

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