Category guide · 2026

Best Nootropic Supplements

Best Nootropic Supplements ranked by clinical evidence, ingredient dosing and manufacturing transparency. Top pick: Thorne Memoractiv (81/100). Updated 2026.

Ranked by science score

  1. Thorne Memoractiv — 81/100 · $42
  2. Nootropics Depot Ashwagandha KSM-66 — 78/100 · $20
  3. Nootropics Depot Longvida Curcumin — 78/100 · $22
  4. Momentous Brain Drive — 73/100 · $40
  5. Mind Lab Pro Universal Nootropic — 72/100 · $69
  6. Nootropics Depot Tongkat Ali 10% Eurycomanone — 72/100 · $30
  7. Jarrow Formulas Citicoline CDP Choline — 69/100 · $18
  8. Real Mushrooms Lion's Mane Extract — 68/100 · $30
  9. Life Extension Cognitex Elite — 67/100 · $36
  10. Performance Lab Mind — 67/100 · $49
  11. Nootropics Depot NMN Powder — 66/100 · $40
  12. Qualia Mind — 62/100 · $139
  13. Nootropics Depot Sleep Support — 62/100 · $25
  14. Nootropics Depot Lion's Mane 8:1 Extract — 61/100 · $20
  15. Four Sigmatic Lion's Mane Elixir — 60/100 · $25
  16. Thesis Personalized Nootropics — 60/100 · $79
  17. NOW Alpha GPC 300mg — 58/100 · $22
  18. Double Wood Supplements Lion's Mane — 58/100 · $23
  19. Alpha Brain by Onnit — 55/100 · $35
  20. Host Defense Lion's Mane Capsules — 53/100 · $25

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